Keywords:
Cardiac, MR-Functional imaging, Computer Applications-Detection, diagnosis, Inflammation
Authors:
B. Baeßler1, G. Michels1, F. Schaarschmidt2, A. Dick1, D. Maintz3, A. Bunck1; 1Cologne/DE, 2Hannover/DE, 3Köln/DE
Methods and Materials
CMR data (Achieva 1.5T,
Philips Healthcare,
Best,
The Netherlands) of 21 patients clinically diagnosed with ACM according to the current recommendations given by the position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases 1 were retrospectively analyzed.
All patients demonstrated inconspicuous CMR findings without any wall motion abnormalities,
signs of edema or early and late gadolinium enhancement (negative Lake Louise criteria 2).
30 age-matched healthy volunteers (HV) served as a control.
Analysis of global longitudinal,
circumferential and radial strain and strain rate (SR) of both ventricles was performed in one long-axis and three short-axis slices using a dedicated FT-software (TomTec Imaging Systems,
Germany; Figure 1).
Statistical analysis was conducted using Wilcoxon rank-sum-test,
one-way robust ANOVA with bootstrapped post-hoc tests,
multiple and multinominal logistic regression analyses,
and ROC-analyses.