Late Gadolinium Enhancement is useful not only in the heart: a new tool to reveal skeletal muscle involvement in idiopathic inflammatory myopathies

Congress:

ESCR 2015

Poster Number:

P-0021

Type:

Scientific Poster

Keywords:

Musculoskeletal system, MR, MR-Diffusion/Perfusion, Experimental investigations, Diagnostic procedure, Inflammation

Authors:

G. Benedetti¹, A. Esposito¹, M. Cava¹, M. colombo¹, G. A. Ramirez¹, D. Velardo¹, A. Manfredi², E. Bozzolo¹, S. Previtali¹, P. Rovere Querini¹, A. Del Maschio¹, F. De Cobelli¹; ¹Milan/IT, ²Milano/IT

DOI:

DOI-Link:

https://dx.doi.org/

Purpose

Late Gadolinium Enhacement (LGE) is commonly used as Magnetic Resonance Imaging marker of myocardial damage in inflammatory cardiomyopathies, like myocarditis and systemic autoimmune diseases. When associated with T2-STIR, LGE allows to distinguish acute from chronic myocardial damage.

Our aim was to verify whether LGE might be as informative in the study of skeletal muscle injury, specifically in inflammatory myopaties, like polymyosistis (PM) and dermatomyositis (DM). Only preclinical study on murine models have been performed until now [Ref.1].