Tissue characterisation, Diagnostic procedure, MR, Cardiac
Z. Szemraj-Rogucka, A. Majos; Lodz/PL
Fifteen patients were considered to meet the criteria for LVNC,
as assessed by CMR.
The mean age was 42 ± 13 years (range,
and 11 patients (73%) were male.
Most of the patients (67%) were seriously symptomatic (New York Heart Association [NYHA] functional classes III/IV).
All LGE(+) LVNC patients and 50% of LGE(−) LVNC patients showed abnormal ECG.
Significant differences were found in the NYHA functional class and age between LGE(−) and LGE(+) LVNC patient groups.
CMR imaging findings
The mean number of non-compacted segments per patient was 6.6 ± 1.6 and the mean NC/C ratio was 4.6 ± 0.9.
The areas of non-compaction were most commonly observed at the apex,
the anterior and the lateral walls,
mainly on their apical and mid-cavity segments (Figure 1).
LGE was present in 11 of the 15 patients (73%).
LGE was observed most frequently in the ventricular septum commonly on basal and mid-cavity segments (Figure 1).
The distribution of LGE was midmyocardial (n = 42; 67%),
subepicardial (n = 11; 18%),
transmural (n = 6; 10%) and subendocardial (n = 3; 5%),
in total of 62 LGE (+) left ventricular segments (Figure 2).
What is significant,
no association was found between late gadolinium enhancement and non-compaction at left ventricular segmental level (phi coefficient 0,021; p= 0,191).