Purpose
4D MR flow is a rapidly evolving technique,
offering both anatomical and functional information in just a single acquisition.
The purpose of this study was to use the anatomical information from the 4D flow sequence,
assess the global left ventricular function and compare the results with the functional cardiac CT acquisitions.
Methods and Materials
Methods
Between November 2015 and February 2016,
we prospectively included 10 consecutive adult patients (4 females,
mean age 35 yo) known with bicuspid aortic valve.
The MR and CT scan were performed in the same day.
The 4D flow raw data sets were uploaded to a dedicated web-based software application (Arterys Inc.,
San Francisco,
CA,
USA).
Images were reconstructed in 20 cardiac temporal phases separately with a compressed sensing algorithm.
The end-diastolic,
end-systolic and stroke volumes and ejection fractions were measured by CMR 4D flow.Functional...
Results
The mean end-diastolic,
end-systolic stroke volumes and ejection fraction were 164(±34) ml,
69(±18) ml,
94 (±19) ml and 58 (±4)% respectively for CMR 4D flow and 183 (±43) ml,
67 (±21) ml,
117 (±25) ml,
64 (±5)% respectively for cardiac CT.
The Pearson’s correlations between CMR 4D flow and CT were 0.91,
0.86,
0.94 and 0.83 for end-diastolic,
end-systolic,
stroke volumes and ejection fraction respectively.
Conclusion
In this study we showed that global left ventricular function can be quantified accurately using CMR 4D flow imaging analysed using a cloud based software