Authors:
O. Unal, N. Toprak, S. Avcu; Van/TR
DOI:
10.1594/ecr2010/C-3264
Conclusion
Our study with high dose (0,2 ml/kg) gadobutrol resulted in a high sensitivity of 95%, and a specificity of 55,4% in the diagnosis of malignant breast lesions (p=0.001), where decreased specificity (regarding enhancement pattern) can lead to an increase in false positive results.
As far as we are concerned, there is no study in the literature concerning CNR of breast lesions on MRI examinations. In our study using gadobutrol, the significant increase in CNR of malignant breast lesions can help in the diagnosis, even in small sized lesions. However, this idea needs further studies with other contrast materials containing gadolinium and also with lower doses of gadobutrol.