Oncology, Genital / Reproductive system female, Pelvis, MR, Chemoembolisation, Staging, Surgery, Neoplasia, Pathology
S. Kharuzhyk, I. A. Kosenko, O. P. Matylevich, T. M. Litvinova, I. S. Dulinec; Minsk Region/BY
In patients with uterine cervix cancer treated with neoadjuvant chemotherapy with uterine arteries chemoembolization the overall tumor response rate (complete response + partial response) was 70% (28/40).
In 5 of 7 complete MRI responses isolated cancer cells were revealed on pathology.
Residual stage IA tumor was not detected by MRI in another 1 patient.
specificity and accuracy of MRI in the detection of stage IA or greater residual tumor were 97%,
100% and 98% respectively.
specificity and accuracy of MRI in the detection of parametrial tumor invasion and pelvic lymph nodes metastases were 73%,
76% and 44%,
Sensitivity of size criterion of 1 cm in a short axis for pelvic lymph nodes metastases detection is low as smaller lymph nodes may be malignant.
MRI has a high accuracy in the preoperative staging of the cervical cancer and in the diagnosis of residual tumor after neoadjuvant chemotherapy.