Breast, Mammography, Experimental, Comparative studies, Experimental investigations, Technical aspects
R. Girometti1, C. Zuiani1, A. Taibi2, S. Vecchio3, R. Fazzin1, M. Bazzocchi1; 1Udine/IT, 2Ferrara/IT, 3Pontecchio Marconi/IT
- State-of-the-art mammography,
including digital mammography (DM),
is of pivotal importance to achieve early diagnosis of breast cancer,
and the only imaging tool proved to reduce mortality .
the overlap of fibro-glandular tissue in dense breasts may affect sensitivity and specificity of DM by masking or mimicking a cancer .
- Digital Breast Tomosynthesis (DBT) is a novel imaging tool aimed to overcome tissue overlap,
since it is based on a moving x-ray source and a digital detector used to obtain a three-dimensional (3D) volume of thin section data.
Images are then reconstructed with proper algorithms to obtain a set of thin image sections parallel to the breast platform .
- DBT is still under investigation.
This technique is expected to help radiologists in improving: (i) lesions detectability; (ii) the characterization of masses and architectural distortions (especially in dense breasts); (iii) the definition of lesions in terms of dimensions and margins [2-3].
The aim of our study was to compare DBT and DM in terms of: (i) diagnostic yield (DY) for cancer (primary endpoint); (ii) the agreement in assessing lesion size (secondary endpoint).