Musculoskeletal spine, Neuroradiology peripheral nerve, Interventional non-vascular, CT, MR, Outcomes analysis, Observer performance, Puncture, Hernia, Outcomes, Image verification
M. Perri, L. Sacchetti, G. Grattacaso, L. M. Gregori, A. V. Giordano, M. Gallucci, C. Masciocchi; L'Aquila/IT
Oxygen-ozone(O2-O3) discolysis is a good alternative to surgical treatment for lumbar disc herniation for patients failing to respond to conservative treatment,
with a successful percentage of 70-80% without complications [1-2].
The basic principle of action of intradiscal injection of oxygen-ozone(O2-O3) mixture,
is the reduction of proteoglicans,
consequent dehydration and shrinkage of the disc but no study has been published on an analysis of these changes in MRI.
Since there is good evidence that DWI has improved diagnostic accuracy for detecting diffusibility water reduction in degenerative disc disease we assumed that DWI and related ADC values could help us in distinguishing a possible change in water content of the discs .
On the basis of these results,
we undertook a prospective trial to assess the usefulness of diffusion weighted imaging (DWI) and the apparent diffusion coefficient (ADC) versus intervertebral disc volumetric analysis(IDVA) for predicting shrinkage of lumbar disc herniation treated with oxygen-ozone(O2-O3) discolysis.