Oncology, Abdomen, Gastrointestinal tract, CT, Contrast agent-intravenous, Staging, Cancer, Metastases, Monoclonal antibodies
A. Insalaco, G. Lo Re, F. Muscarneri, F. Patti, M. C. Galfano, L. La Grutta, T. V. Bartolotta, M. Midiri; Palermo/IT
Methods and Materials
In the period between April 2011 and March 2012 were evaluated CT scans of six women aged between 45 and 75 with GIST at an advanced stage with the presence of liver metastases.
Criteria for inclusion were evidence of disease that was unidimensionally measurable with CT; failure of previous treatment; adequate hepatic,
and cardiac function.
Exclusion criteria were renal insufficiency (serum creatinine greater than 2 mg/dL),
pregnancy and documented allergic reaction to iodinated contrast agent.
Patients were observed by MSCT after c.m administration,
before start of TKI treatment and after 3 and 6 months.
For each patient were identified at least 3 liver lesions as target.
For each of them were measured the maximum diameter and the HU densitometric average values in venous phase (by positioning of at least 3 ROI).