Keywords:
Congenital, Imaging sequences, MR, Cardiac
Authors:
G. Gentile1, G. Aquaro2, E. Grassedonio1, G. Todiere2, P. Toia1, L. La Grutta1, C. Tudisca3, M. Lombardi2, M. Midiri1; 1Palermo/IT, 2Pisa/IT, 3Palermo, PA/IT
DOI:
10.1594/ecr2013/C-1861
Methods and Materials
23 patients (16 men; age 42+14) with known HCM and 42 HC (19 men; age 41+17) were enrolled in this prospective and multicentric study (University Hospital “P.
Giaccone” – Palermo; “G.
Monasterio” Foundation,
National Council of Research - Pisa).
Atrial and ventricular function was studied through cine SSFP (Steady State Free Precession) MRI sequences on Short Axis (SA) view including the left ventricle and all of the left atrium.
Image analysis was performed using the software Tracking Tool (validated by Lionetti et al.
AJP 2007) (Fig.1-2).
Fig. 1: Screenshot of the software used for atrial function analysis
References: Giovanni Gentile MD
Fig. 2: Screenshot of the software used for ventricular function analysis
References: Giovanni Gentile MD
The atrial and ventricular dV/dT curves derived from Volume/Time curve (Fig.
3).
Fig. 3: Ventricular and atrial Volume/Time curves (A-B) and derived dV/dT curves (C-D)
References: Giovanni Gentile MD
The duration of the different cardiac phases was converted in millisecond by the formula: (60000/(30*Heart Rate).
The diastolic parameters were extrapolated from dV/dT curves.