Screen-Film Mammography had a great impact in breast cancer detection, thanks to its possibility of early diagnosis, that leads to mortality reduction [1]. Moreover mammography represents the only imaging tool, which permits to reduce mortality [2]. Digital Mammography (DM) represents an evolution of Screen-Film Mammography, that demonstrates to have similar overall diagnostic accuracy of film mammography, but digital mammography is more accurate in women under the age of 50 years, women with radiographically dense breasts, and premenopausal or perimenopausal women [3] . However, the overlap...

Population During a 7 months period (from November 2011 to may 2012) we retrospectively obtained 51 surgical specimens (44 mastectomies and 7 quadrants) from 51 patients with an age range 40-86 (mean age 60.5 years). We chose only specimens with thickness of at least 2 cm, that was the less thickness required to perform DBT. For this reason the number of mastectomy in our study population was higher than the one of quadrantectomy. All patients referred to surgery for a histological proved breast cancer obtained...

A total of 67 malignant lesions were found at the histopathological analysis of the specimens. Of these lesions 32 were Invasive Ductal Carcinomas (IDCs), 5 Ductal Carcinomas In Situ (DCISs), 15 Ductal Carcinomas In Situ + Invasive Ductal Carcinomas (DCISs+IDCs), 9 Invasive Lobular Carcinomas (ILCs), 2 Lobular Carcinomas In Situ + Invasive Lobular Carcinomas (LCISs+LDCs) and 4 rare histotypes (TAB 1). Regarding rare histotypes 2 were Mucinous Carcinomas, one was a Papillary Invasive Carcinoma and one was a Apocrine Breast Carcinoma ( Table 1). Concerning...

This study done on surgical specimens demonstrates as DBT showed a higher DY than DM in malignant lesion detection. DBT recognized a greater number of cancers compared to DM. DBT recognized 11 lesions not seen with DM. DM, on the contrary, recognized 5 lesions not showed by DBT. Both techniques missed 4 lesions, that were 2 small (< 10 mm) IDC, a DCIS and a IDC + DCIS with a mean diameter of 16.2 mm. DBT showed also a statistically significant higher detectability score, that...

Tabar L, Vitak B, Chen HH, et al. The Swedish Two-County Trial twenty years later. Updated mortality results and new insights from long-term follow-up. Radiol Clin North AM 2000 Jul;38(4):625-51. Kolb TM, Lichy J, Newhouse JH. Comparison of the performance of screening mammography, physical examination, and breast US and evaluation of factors that influence them: an analysis of 27,825 patient evaluations Radiology 2002; 225(1): 165-75. Pisano ED, Gatsonis, Hendrick E, et al. Diagnostic performance of digital versus film mammography for breast-cancer screening. N Engl J...