Keywords:
Tissue characterisation, Cancer, Diagnostic procedure, Computer Applications-Detection, diagnosis, MR-Diffusion/Perfusion, MR, MR physics, Breast
Authors:
F. Borlinhas1, H. A. Ferreira2; 1Lisboa/PT, 2Lisbon/PT
DOI:
10.1594/ecr2013/C-2510
Results
- Benign vs.
Malignant breast lesions
Benign lesions showed higher ADC,
D and D* mean values than malignant lesions.
On the other hand,
PF mean values were observed to be higher in malignant tissues than in benign tissues (Table 1 and Fig. 4).
Significant differences were observed in ADC and D (p=0.007 and 0.005,
respectively) between benign and malignant lesions.
No other significant differences were observed.
- Histological lesion types – FA vs.
IDC vs.
DCIS
FA lesions showed higher ADC,
D and D* mean values than IDC or DCIS lesions,
while they showed intermediate PF mean values.
IDC lesions showed higher D* and PF mean values than DCIS lesions,
and IDC showed lower values than DCIS lesions regarding ADC and D parameter (Table 2 and Fig. 5).
Significant differences in ADC and D were found between FA and IDC lesions (p=0.007 and 0.005,
respectively) and also between FA and DCIS lesions (p=0.033 and 0.032,
respectively).
Significant differences were also found in PF between IDC and DCIS lesions (p=0.041).
- IDC lesions – G1 vs.
G2 vs.
G3
It was observed that G3 IDC lesions showed higher ADC and D values than lesions in other grades.
G1 lesions showed higher D* values and G3 showed the lowest D* values.
PF values were higher for G2 and lower for G1 lesions.
(Table 3 and Fig. 6).
No significant differences were found between lesion grades.