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Keywords:
Breast, Percutaneous, Biopsy, Cancer
Authors:
P. Merino Rasillo, E. Ortega García, P. Alonso Bartolomé, S. M. Sanchez Gomez, S. Sánchez Bernal, A. Vega Bolivar; Santander/ES
DOI:
10.1594/ecr2015/C-0644
Methods and materials
Study population
We reviewed our database of all stereotactically (n=1181) vacuum assisted biopsy procedures performed in our hospital between December 2003 and December 2010.
We included in the study 175 lesions (169 patients) in which the pathologic examination of 11G stereotactic VAB samples obtained after the biopsy of microcalcifications revealed a high risk lesion.
All 175 lesions underwent surgical excision (n=125) or a minimum of 2 years´ imaging follow-up (n=50).
The patient´s age,
personal history of breast cancer,
clinical presentation (if the lesion was palpable),
mammographic breast composition,
lesion size,
BIRADS classification,
percentage of lesion removal in case of calcifications,
histopathology results if the patient underwent surgery or imaging follow-up if not were recorded.
Underestimation was defined as lesions yielding a diagnosis of high-risk lesion at stereotactic VAB and carcinoma at excisional surgery (performed immediately after VAB or during the follow-up period due to changes at site of VAB).
Mammographic technique
Bilateral mammography was performed with a dedicated film-screen mammographic equipment (Senix 800 T; GE Healthcare,
Milwaukee,
USA) from December 2003 to February 2005 and with a FFDM unit (Senographe 2000D,
GE) from March 2005 to December 2010,
with magnification views obtained in all cases.
Biopsy
All VAB were obtained under stereotactic guidance (Fischer stereotactic table) using the 11G Mammotome® Vacuum Biopsy System (Ethicon Endosurgery,
Johnson & Johnson).
Specimen radiographs were obtained in all cases and a clip marker was deployed at the site of biopsy in cases of complete removal of the lesion.
Regular mammogram after each stereotactically guided biopsy was also performed.