The stenotic rate (SR) in each PVS group was respective: group B (44.82±5.23)%, group C (59.34±4.07)% and group D (69.46±2.17)%, significant differences were observed between every two groups (P<0.05).

DR increased with the aggravating stenosis degree, and on the 3^rd and 7^th day, group C and D were significantly greater than group B (P<0.05). The PVV_post in PVS groups were significantly higher than group A (P<0.05) on the 3^rd and 7^th day, but no statistical differences between PVS groups were observed. VR of group D was greater than group B and C (P<0.05) on the 1^st day, and kept high till the 3^rd day (P<0.05).      

ALT, AST and TBIL of all experimental groups increased rapidly on the 1^st day, which were significant higher than SOR (P<0.05), and fell abruptly on the 3^rd day. Until the 7^th and 14^th day, ALT and AST almost recovered to normal level, leaving TBIL of group D at a high one, which was still higher than SOR on the 14^th day (P<0.05). The ALB of each experimental group decreased after operation, and went down to the lowest on the 3^rd day (P<0.05 vs SOR).

The LRR of group A and B reached above 90% on the 14th day, leaving group C and D remained respective (83.36±27.32) % and (70.99±5.71) %. PCNA in PVS groups increased on the 1st day after operation and peaked on the 3^rd day, then fell (Fig 3). While, it kept low expression in group D in the whole experiment. The results of linear regression analysis showed a negative correlation between DR, VR and LRR, whose correlation coefficient was respective -0.509 and -0.522(Fig 4;5).