Among 43 patients studied: 19 (44.2%) underwent ultrasound plus mammography to examine mammary finding; 11 (25.58%) underwent ultrasound only; 13 (27.9%) have not continued follow-up.
Among 19 patients who underwent both procedures: in 8 (42.1%) both mammography and ultrasound were negative; in 10 (57.9%) both mammography and ultrasound were positive; in 1 (11.1%) case it is observed only the positive of ultrasound.
Among 11 patients who underwent ultrasound only: 6 have not underwent biopsy because the ultrasound alone showed a benign finding; the remaining 5 positive patients have performed histological study using Tru-cut.
Therefore among 30 patients who have examined mammary finding:
- 8 (26.7%) showed no morphological abnormalities in the mammary parenchyma;
- 22 (73.3%) showed positive finding (benign or malign) to radiological imaging.
Diagnostic or histological results of the 22 positive patients were: 9 invasive ductal carcinoma (CDI),
4 lymphoma,
1 cystoadenocarcinoma,
1 carcinomatous mastitis,
6 fibroadenoma,
1 phylloides tumor (Table 2).
Among 22 positive patients,
we have evaluated concordance among SUVmax value detected and diagnostic and/or histologic result.
7 patients (31.8%) had SUVmax ≥ 2.5; 15 patients (68.2%) SUVmax < 2.5.
SUV average value results 2.0233 (SD ± 2.38,
minimum value 0.60,
maximum value 15.70),
(Table 3).
SUV value tends to be higher in the malignant lesions (Table 4).
Using Non-parametric Test of Median and Mann-Whitney U Test,
does not seem to exist a statistically significant correlation between SUV and malignancy of breast lesion.
Among incidental mammary 18F-FDG uptake the incidence of malignant lesion was 68.2%,
of benign lesion was 31.8%.
13 patients have not examined mammary finding: 4 are dead,
9 were lost during follow-up.
In 1 of these cases not investigated,
after 1 year from PET/CT,
we found a breast cancer exactly in the setting of 18F-FDG uptake.