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Head and neck, Thyroid / Parathyroids, Ultrasound, Ultrasound-Colour Doppler, Ultrasound-Spectral Doppler, Treatment effects, Endocrine disorders
T. A. R. R. dos Santos, T. Romero, R. C. L. Coêlho, S. M. Tochetto, M. C. Chammas; Sao Paulo/BR
Methods and materials
Fifty patients with Graves' disease were consecutively selected,
of both gender,
with no age distinction,
with positive clinical and laboratorial findings of the disease and no prior radioiodine therapy.
This prospective study was conducted with IRB approval,
after written informed consent be obtained from all participants.
An ultrasonography evaluation of the thyroid gland was performed before and after 131I therapy (1,
3 and 6 months).
The following aspects were evaluated: thyroid volume and parenchyma echogenicity,
echotexture and vascularization.
A systolic peak velocity for the inferior thyroid arteries was measured.
All examinations were performed by the same observer in the Department of Radiology,
University of São Paulo,
The examinations were performed using the Philips IU 22 (Philips Ultrasound,
Bothell WA ,
2009) and a linear transducer (5-12 MHz).
The statistical analysis was performed on MedCalc (Mariekerke,
A P value < 0.05 was considered significant.