Aims and objectives
One of the most severe forms of psoriasis which significantlydecreases the patients' life quality is the joints damage – Psoriatic arthritis (PsA).
According to the different authors data it varies from 5 to 47 % among all the cases of skin and joints simultaneous lesions [1–4].
Along with this,
PsA is diagnosed in 5–13 % patients with early-stage inflammatory joints diseases [2,
4].
It was found out that about 60–70 % of psoriasis cutaneous manifestations precede the arthritis and only in 10–20 % of cases...
Methods and materials
The group of 26 patients with determined diagnosis of PsA in anamnesis and with diagnostically significant indicators in accordance with CASPAR classification was formed.
Among them there were 10 women and 16 men at the age from 24 to 65.
According to anamnestic data the duration of articular pain syndrome was 17.2 ± 1.9 months,
the amount of body surface area (BSA) was 9.8 ± 2.6 %,
the psoriasis severity index (PASI) came to 12.1 ± 3.2,
and dermatological quality of life index (DQLI) became...
Results
SR data allowed revealing the characteristic signs of PsA symmetric polyarthritis variant (n = 15) and mutilans (osteolitic variant) form (n = 11) in wrists and hands: irregular narrowing of the joint spaces due to ankylosis,
erosions of the articular surfaces,
bony proliferation in the form of ossification in the interphalangeal ligaments and enthesophites.
Arthritis mutilans form was represented mostly by osteolysis with severe damages of bones surfaces.
High spatial resolution and wide range of CBCT images post-processing allowed identifying and determining the precise localization...
Conclusion
Taking into account low radiation dose,
high spatial resolution with the ability to identify even less than 1 mm bone structural remodeling,
and relatively low direct cost of the study,
CBCT could be considered as a first stage method for the diagnosis characteristic changes of the hand and wrist bones and joints in patients with PsA.
Additionally,
this technique could be used in dynamics,
while monitoring the therapy effectiveness,
replacing gradually SR.
Application of the standardized protocol for hand and wrist CBCT in patients with...
References
1. Korotaeva T.
V.
Psoriatic Arthritis: Clinic,
Diagnostics,
Pathogenesis,
Treatment,
Markers of Cardiovascular Risk.
Nasonov E.
L,
editor.
Moscow: NPO «Media-Grafika».
2013; P.
309.
(in Russian)
2. Krasnenko S.
O.,
E.
Yu.
Loginov,
A.
V.
Smirnov Clinic-Radiodiagnosis of Early Peripheral Psoriatic Arthritis.
Nauch – practic.
reumatol.
2012; 52 (3): 97–100.
(in Russian)
3.
Mishina O.
S.,
A.
S's Janitors.,
Dontsova E.
V.
Morbidity of Psoriasis and Psoriatichesky Arthritis in Urban and Country People of the Russian Federation.
The bulletin of new technologies.
2012; 1: electronic...