The purpose of this educational exhibit is to: 1. Describe and illustrate the MDCT imaging findings of kidney parenchymal changes in patients with alcohol surrogate abuses; 2. Provide relevant data on the pathomorphology and clinical manifestations in this patients; 3. Describe the use of contrast enhancedmultiphase MDCT techniques in the differentiation of chronic toxic changes in renal parenchyma with other conditions accompanied by atrophic changes; 4. Present our experience in studying such patients in past 4 years.

Consumption of surrogate alcohols (i.e., nonbeverage alcohols and illegally produced alcohols) was shown to impact on different causes of death, not only poisoning or liver disease, and appears to be a major public health problem in Russia, Eastern Europe's countries and elsewhere. Surrogate alcohol - different types of liquids, which are not intended for internal use, but, nevertheless, is used instead of alcohol. There are many other toxic substances in surrogate alcohol besides ethanol, such as hydrogen peroxide, antiseptics, ketones,as well as alcohols other than...

Twenty two adults (mean age 45.2 years, range 37.2-64.1years) with same anamnesis, clinical laboratory and ultrasound data underwent multidetector contrast enchanced CT in our department between November 2012 and September 2016. All examinations were performed with a 16-slice MDCT imaging system (Siemens Somatom™ Emotion 16; Siemens Healthcare, Germany) with a standard contrast dose intravenously injected by Medrad™ injector. In thirteen of twenty two cases CT pattern was quite similar: marked cortical thinning and irregularity (arrows)in combination with normal renal parenchyma on both sides.

Multiphase MDCT is a powerful diagnostic tool in direct accessing the amount of damage of kidney parenchyma in patients with renal failure caused by repeated episodes of drinking alcohol surrogates history and arise as an additional evident factor in the prognosis of the disease in these patients, which is very important for clinicians.

Alexey Kokunin M.D., radiologist Regional Diagnostic Center, MRI Department (Nizhniy Novgorod, Russia); Balakhna Central Regional Hospital, Chief of Radiology department(Balakhna, Russia); E-mail to contact: [email protected]

Lachenmeier DW,Rehm J,Gmel G.Surrogate alcohol: what do we know and where do we go?Alcohol Clin Exp Res.2007 Oct;31(10):1613-24. Epub 2007 Aug 6; Stonys A,Kuzminskis V,Seputyte A,Astasauskaite S,Jeseviciūte AAcute renal failure in patients with alcoholic surrogate intoxication.Medicina (Kaunas).2007;43 Suppl 1:36-9. Edmondson HA, Reynolds TB, Jacobson HG. Renal papillary necrosis with special reference to chronic alcoholism. A report of 20 cases.Arch Intern Med 1966; Arora V, Nijjar IB, Multani AS, Singh JP, Abrol R, Chopra R, et al. MRI findings in methanol intoxication: A report of two...