Aims and objectives
In the last decades a particular attention was paid to the identification of early markers of asymptomatic target organ damage,
such as left ventricular hypertrophy in arterial hypertension,
because they allow early evaluation of global cardiovascular risk.
In this way,
the aim of our study is the evaluation of the association of intrarenal hemodynamics with ambulatory blood pressure values,
left ventricular geometry and left ventricular hypertrophy.
Methods and materials
The population of our study were 65 patients (30 females and 35 males, mean age 45,3 years +/- 9,2 years) with grade I-III arterial hypertension.
In all subjects careful clinical history and physical examination were performed.
Blood pressure was recorded following the recommendations of the 2013 European Society of Hypertension/ European Society of Cardiology Guidelines.
All participants underwenta complete echocardiographic study,
ambulatory blood pressure monitoring and color Doppler echography ofrenaland intrarenal arteries.
After therenalDoppler waveform was obtained,
the renalresistiveindex (RRI)was calculated by peak systolic velocity...
The mean RRI was 0,685 (p<0,01),
mean ambulatory systolic blood pressure (SBP) was 135,6 mmHg,
mean ambulatory diastolic blood pressure (DBP) was 77 mmHg,
(mean daytime SBP 141,96 mmHg,
DBP 82,07 mmHg, mean nighttime SBP 128,67 mmHg,
DBP 71,92 mmHg).
The mean pulse pressure (PP) was 59,1 mmHg.
RRI was negatively related to ambulatory DBP (r = -0.339,
p < 0.05),
heart rate (r=-0.326,
p<0.01) while it was positively associated with ambulatory SBP (r = 0.659,
p < 0.05),
ambulatory PP (r = 0.366,
In hypertensive patientsRRI,
which is considered an expression of arterial impedance,
has a good correlation with the blood pressure values,
left ventricular geometry and the presence of left ventricular hypertrophy.
These may suggest that RRI,
provides a noninvasive parameter in the followup of the patients with arterial hypertension.
the evaluation of the RRI could facilitate the prediction of early cardiovascular damage and provide a fair assessment of the cardiovascular risk.
Comment on the Paper by Cauwenberghs and Kuznetsova Entitled Determinants and Prognostic Significance of the Renal Resistive Index.
2016 Apr; 3 (3-4): 179–181.
Increased renal resistive in- dex in patients with essential hypertension: a marker of target organ damage.
Nephrol Dial Transplant.
2014 Feb; 14(2):360-5.
Mild renal dysfunction and renal vascular resistance in primary hypertension.
Am J Hypertens.