Keywords:
Cardiovascular system, Cardiac, Contrast agents, CT-Angiography, MR-Angiography, CT, Ablation procedures, Computer Applications-3D, Education, Cardiac Assist Devices, Congenital, Ischaemia / Infarction
Authors:
O. Y. Dariy, S. Aleksandrova, V. Bereznitskiy, L. Yurpol’skaya, V. Makarenko, L. Bockeria; Moscow/RU
DOI:
10.1594/ecr2018/C-0278
Results
Paroxysmal and permanent type of atrial fibrillation we obtained in 17 (n=68%) patients.
Table1.
CMR characteristics of Patients with HCM
|
Patients with HCM and AF (1-st group)
|
Patients with HCM and AF (2-d group)
|
р- values
|
LV EF (%)
|
68 ± 10,1
|
73,8 ± 8,78
|
р= 0,46
|
LV EDV (ml)
|
122,4 ± 25,5
|
112 ± 24
|
р= 0,34
|
LV ESV (ml)
|
30 ± 12
|
26 ± 6
|
р= 0,61
|
LV-EDMI (g/m2)
|
111,5 ± 39,1
|
86,7 ± 29
|
р= 0,32
|
LA (mm)
|
58,4 ± 4,6
|
43,6 ± 5,6
|
р= 0,008
|
LA volume (ml)
|
110,6 ± 25,1
|
72,7 ± 13,7
|
р= 0,002
|
MAPSE (mm)
|
6,9 ± 1,8
|
11,6 ± 0,8
|
р= 0,0001
|
Presence of ≥ moderate mitral regurgitation (n)
|
n=13
|
n=3
|
р= 0,01
|
LGE (%)
|
13,6 ± 14,5
|
7,2 ± 8,8
|
р= 0,8
|
LV-RI (g/ml)
|
2,12 ± 0,4
|
1,63 ± 0,36
|
р= 0,005
|
Data are presented as ± standard deviation.
EDMI= end diastolic mass index,
MAPSE = mitral annular plane systolic excursion. LVRI= left ventricular remodeling index.
Mean native IAS myocardial T1 value in patient with AF was around 1649±141ms (1st group),
that was significantly higher than the mean in patients group without AF (2d group) 1412±73ms (p<0,05).
Post-contrast IAS T1 value was shorter in the 1st group of patients (319±42ms) than in the 2d group (344±65ms) (p<0,05).
ECV IAS in the 1st group of patients was (54,08±7%),
in the 2d group around (51,6±8%).
We identified increase of LA volume in the 1st group of patients (102±19ml) compared with the 2d group ((66±12,7ml),
p<0.05).
Univariate analysis of two groups of patients identified moderate positive correlation of AF as native T1 as ECV (r=0,679,
p<.05).
High positive correlation of AF and LA volume r=0,739,
p< .05.
Post-contrast atrial blood pool T1 time was not significantly different between patients with AF and those without AF (r= 0,18).
ROC curve analysis showed a good model for the estimation of AF,
the highest AUC presented at IAS native T1 of 1410,0 (0,806;p= .02) and LA volume 78,79 ( 0,872; p=.02)