Lung, Thorax, Interventional non-vascular, CT, Percutaneous, Biopsy, Complications, Cancer, Economics
V. Fernandez-Lobo1, J. A. Parra1, A. B. Barba Arce2, E. herrera romero3, E. Montes Figueroa1, E. YLLERA CONTRERAS4, C. Jimenez Zapater1; 1Santander/ES, 2Torrelavega, Cantabria/ES, 3Santander, Cantabria/ES, 4Burgos/ES
Methods and materials
Six hundred and two cases of the Hospital Universitario Marqués de Valdecilla (Santander,
Spain) chest database were used to retrospectively select all TTNB performed in patients over the last 5 years of age between May 1,
and April 31,
The selected TTNB specimens were classified as follows: “malignant disease” for cases of histologically proven malignancy; “nonmalignant disease” for those with an identified but nonmalignant disease; and “without malignancy (negative) result” for those with no disease diagnosed.
Malignant results were not further investigated.
The patients with nonmalignant results (54) were followed at least 2 years,
to verify if they received a second biopsy,
and if there were differences between the first and the second procedure.
The pathologic agreement rate between the initial and repeat TTNB was also evaluated.
The main population characteristics are in the Fig. 1 .
All TTNBs were permorfed by radiologist with at least 5 experience years.
Patient position was determined according to the location of the lession in the thorax.
Coaxial systems using semiautomated core-biopsy needles (18G) were used.
All TTNBs were performed under CT scan guidance.
Once the biopsy was completed,
a whole-thoracic CT scan was performed to check for acute complications such as pneumothorax or bleeding.
The normal distribution of continuous variables was assessed by the Kolmogorov-Smirnov test.
Categorical variables were expressed as percentages.