Aims and objectives
The prognosis of different histologic subtypes of renal cell carcinoma (RCC) varies and affects management.
Patients with chromophobe or papillary RCC have better prognosis than those with clear cell RCC.
The other factor that may affect the management of the disease,
which is the nuclear grade of the tumor.
Grade is an independent risk factor important for patients survival.
The aim of our study was to study the utility of diffusion-weighted imaging (DWI) in the prediction of renal cell carcinoma subtypes and prediction of tumor...
Methods and materials
The Institutional Review Board approved this retrospective study,
and informed consent was waived.
PACS (Picture archiving and communication system) was reviewed from August 2012 to May 2017 and 36 patients underwent renal intervention and had a histopathological diagnosis of the various renal disease were obtained.
surgery or tru-cut biopsy is performed for renal mass in 27 patients.
Two patients were excluded from the study as their histopathological results showed pathology other than RCC,
including angiomyolipoma in 1 patient and transitional cell carcinoma in...
Twenty five renal masses were evaluated in 25 patients,
they were 17 male and 8 female,
their age ranged from 38 to 81 years,
mean age 56,04±11,30.
Fourteen masses underwent radical nephrectomy and ten masses underwent partial nephrectomy while true cut needle biopsy was done for one mass.
Pathologic confirmation of these 25 renal masses had obtained with 21 diagnosed as clear cell RCCs,
3 as papillary RCCs and 1 as chromophobe RCCs.
The Mean dif-ADC value was significantly higher than sel-ADC value.
DWI may be useful in the preoperative characterization of RCC.
The mean ADC value may thinks as a helpful imaging tool in them differentiation between subtypes of RCC and predict of tumor grade.
We need to study with more patients on this topic.
Contrast enhanced MRI and Diffusion Weighted Imaging (DWI) in the evaluation of renal cell carcinoma and differentiation of its subtypes.The Egyptian Journal of Radiology and Nuclear Medicine.
Renal cell carcinoma: applicability of the apparent coefficient of the diffusion-weighted estimated by MRI for improving their differential diagnosis,
and differentiation grade.International urology and nephrology,49(2),