Keywords:
MR-Diffusion/Perfusion, MR, Kidney, Abdomen, Diagnostic procedure, Tissue characterisation
Authors:
S. Thiravit, P. Suwanchatree , V. Suvannarerg; Bangkok/TH
DOI:
10.1594/ecr2018/C-1131
Conclusion
In our study,
we performed MRI by using 3-T scanners and diffusion gradient b values of 0,
50,
500 and 750 s/mm2,
which was different from the previous studies [2-5].
We evaluated the patients with CKD and demonstrated a weak linear correlation between renal ADC values and eGFR.
We also found the significant different between mean ADC values in CKD patients with moderate-severe reduced renal function (eGFR,
< 60 mL/min/1.73m2) versus those with normal or mild reduced renal function (eGFR,
≥ 60 mL/min/1.73m2).
To differentiate between stage 2 (eGFR,
60–89 mL/min/1.73m2) and stage 3 (eGFR,
30–59 mL/min/1.73m2) of CKD,
this has a potential to be helpful in clinical practice,
because nephrologists would take more caution in a treatment of patients with stage 3 CKD such as vigilant control of blood pressure and other risk factors.
However,
post hoc analysis cannot demonstrate the significant difference between moderate reduced renal function (eGFR,
30–59 mL/min/1.73m2) and severe reduced renal function (eGFR,
≤29 mL/min/1.73m2),
which may be due to a small number of patients in the severe group.
In conclusion,
an ADC value of renal parenchyma has a potential to be a marker for determination of CKD patients with normal-mild reduced renal function (eGFR,
≥ 60 mL/min/1.73m2) versus those with moderate-severe reduced renal function (eGFR,
<60 mL/min/1.73m2).
This determination could be helpful to clinical practice.