Keywords:
MR-Diffusion/Perfusion, MR, Kidney, Abdomen, Diagnostic procedure, Tissue characterisation
Authors:
S. Thiravit, P. Suwanchatree , V. Suvannarerg; Bangkok/TH
DOI:
10.1594/ecr2018/C-1131
Results
The study comprised of 216 patients with CKD (132 men,
84 women; aged 20 to 88 years and mean age was 62.39 years) which were 72 (33.3%),
82 (38%),
46 (21.3%) and 16 (7.4%) patients in grouped stage 1,
2,
3 and 4,
respectively.
Correlation between ADC values and eGFR
The study showed a significant linear correlation between the ADC values and eGFR in the patients with CKD (r=0.254,
p<0.001) (Table 1) (Figure 2).
Analysis of ADC values at different grouped stages of CKD
The mean with standard deviation,
median,
minimum and maximum of ADC values according to group stages of CKD were described (Table 2).
In subgroup analysis,
the mean ADC values of the CKD patients in grouped stage 1 were statistically significant higher than those in grouped stage 3 (p < 0.01),
as well as the mean ADC values of the CKD patients in grouped stage 2 were statistically significant higher than those in grouped stage 3 (p < 0.01).
There is no significant difference between mean renal ADC values of CKD grouped stage 1 and 2 patients (p = 0.503),
CKD grouped stage 1 and 4 patients (p = 1.0),
CKD grouped stage 2 and 4 patients (p= 1.0) and CKD grouped stage 3 and 4 patients (p = 0.484) (Table 2).
Comparison of ADC values in patients with grouped stage 1-2 versus grouped stage 3-4 CKD
As divided patients into 2 groups by using eGFR cut-point of 60 mL/min/1.73m2,
paired comparison showed the mean ADC values of the patients with grouped stage 1-2 CKD (eGFR,
≥60 mL/min/1.73m2) was statistically significantly higher than those with grouped stage 3-4 CKD (eGFR,
<60 mL/min/1.73m2) (p < 0.01) (Figure 3).