Aims and objectives
Ductal Carcinoma In Situ (DCIS) is a noninvasive malignancy of the breast that accounts for approximately 25% of all diagnosed breast cancers [9].
It's the result ofintraductal proliferation of malignant cells without evidence basement membrane invasion.
The classic imaging finding aresuspicious microcalcifications detected at mammography,
which representsaround 90% of cases [5].
The imaging presentation as a breast mass was thought to be rare in earlier studies,
approaching 10% of cases [5],
but has become an increasingly recognized entity in more recentstudies [4].
The purpose of...
Methods and materials
In this retrospective,
descriptive study all patients who underwent surgery in our institution for pure DCIS during the period of january 2015 and march 2017 were included (total of 467 patients).
Those cases that presented as masses in any breast imaging modalities were further selected,
with a total of 11 women (ages 46-72,
mean age 56).
Patients whose lesions had aninvasive component at biopsy or had DCIS as an incidental finding were excluded.
MR and US studies were available for all patients,
but mammography was...
Results
Of a total of 467 operated breast cancers,
41 cases of pure DCISwere identified (8,7%),
11 of them (26.8%) presentedas a masson either US or mammography.
Two cases (22.2%) were US-only lesions.
Mammography
Images were available for 9 out of 11 patients.
In two cases studieswere normal.
Masses were detected in 4 patients (44.4%),
most frequently associated with microcalcifications (3 cases).
The remaining cases presented as microcalcifications,
isolated in 2 cases and associated with a focal asymmetry in 1 case.
Ultrasound
In US 6/11 (54,5%)...
Conclusion
Pure DCIS presenting as a mass is a more common scenario than previously thought,
representing 26.8% of cases in our series.
Almost half of them were low/intermediate suspicion lesions in US.
Coalesced mammary ducts distended by malignant cells are responsible to the macroscopic nodular appearance.
Personal information
C.
Darrás,
MD
Servicio de Imágenes Mamarias,
Clínica Alemana de Santiago
Santiago - Chile.
Mail:
[email protected]
References
Dershaw,
D.,
Abramson,
A.,
& Kinne,
D.
(1989).
Ductal Carcinoma in Situ: Mammographic Findings and Clinical Implications.
Radiology ,
411-415.
Ikeda,
D.,
& Andersson,
I.
(1989).
Ductal Carcinoma in Situ: Atypical Mammographic Appearance.
Radiology ,
661-666.
Park,
J.-S.,
Park,
Y.-M.,
& Kim,
E.-K.
(2010).
Sonographic Findings of High-Grade and Non-High-Grade Ductal Carcinoma in Situ of the Breast.
Journal of Ultrasound in Medicine ,
1687-1697.
Scoggins,
M.,
Fox,
P.,
& Kuerer,
H.
(2015).
Correlation Between Sonographic Findings and Clinicopathologic and Biologic Features of Pure Ductal Carcinioma...