Keywords:
Tissue characterisation, Diagnostic procedure, Ultrasound, Breast, Soft tissues / Skin, Ultrasound physics
Authors:
S. Sanabria, K. Martini, M. Rominger, K. Dedes, D. Vorburger, T. Frauenfelder, O. Goksel; Zurich/CH
DOI:
10.1594/ecr2018/C-1388
Methods and materials
Ten women with biopsy-proven lesions (4 invasive ductal carcinoma,
5 fibroadenoma,
1 cyst; mean age 70 yrs) were examined with hand-held SoS-US using a commercial ultrasound system (SonixTouch,
Ultrasonix,
Richmond,
CA) (Fig.
1).
B-mode imaging was used for lesion localization (Fig.2a).
Hand-held SoS-US (Fig.
2b) uses a passive plexiglass reflector positioned opposite to the breast was used as a timing reference for the signals transmitted through the lesions [9-10].
Synthetic aperture data was acquired and average speed of sound (SoS) values across the lesions were measured.
The SoS variations in breast lesions were recorded with an accuracy of 0.7%.
Elastography was performed for 5 of the lesions (3 IDC,
1 FA,
1 cyst) with a GE Logiq E9 machine.
Shear wave velocity (SWV) and strain ratios (SR) were recorded for the lesions.
Finally,
a healthy volunteer (42 yr) without breast lesions was repeteadly assessed with SoS-US and SWV at five different breast compression levels.
The examinations were performed in cranio-caudal view and retromammillar segment for both non-diseased breasts.
For each breast,
the distance between reflector and probe was gradually changed (see Fig.
1) and SoS was measured.
Then the same procedure was repeated for SWV.