Cancer, Computer Applications-Detection, diagnosis, CT, CAD, Thorax, Respiratory system
M. Hall1, A. A. A. Setio2, S. Sheridan1, M. Sproule1, M. Williams3, E. T. Scholten4, C. Jacobs4, B. Van Ginnekin4, G. Roditi1; 1Glasgow/UK, 2nijmegen, Gelderland/NL, 3Edinburgh/UK, 4Nijmegen/NL
Methods and materials
The initial screening Chest CT scans from Glasgow patients enrolled within the prospective ECLS study5 were sent for Lung-RADs analysis by Diagnostic Image Analysis Group Department of Radiology and Nuclear Medicine,
Radboud University Medical Center.
Computer aided detection was used to identify nodules and then categorise them into one of four groups (CAD 1 - 4) based upon probability of malignancy taking into account lesion morphology,
location and texture.
Independently and blind to the CAD results the scans were reported by two experienced consultant respiratory radiologists and assigned a similar grading category.
The patient were then followed up with interval CT scans as per the ECLS study protocol.