Aims and objectives
The aim of our study was the retrospective evaluation of 70 Random Prostate Biopsies (RPB).
13/70 biopsies were performed with Target Fusion Imaging (TFI).
The assessment of the different results between the two proceduress in percentage of positivity was also obtained.
TFI with a minimum number of samples in terms of positivity is able to prove the same effectiveness of RPB if the biopsy procedure is anticipated by a multiparametric-Magnetic Resonance Imaging (mp-MRI) that allows the building of a prostatic lesions "mapping" with the option...
Methods and materials
70 patients receiving biopsy with PSA value between 4.5 and 10 ng /ml with suspected PSA ratio,
negative for Digital Rectal Examination (DRE) and Trans-Rectal Ultrasound (TR-US).
From January 2016 to February 2017,
a working group including the Urology Unit of the S.
Eugenio Hospital ASL Roma 2 and the Diagnostic and Interventional Radiology Unit of S.
Filippo Neri Hospital ASL Roma 1,
performed 70 prostate biopsies in patients with clinical suspicion of Prostatic Cancer.
57/70 patients were evaluated with 12 randomized cores.
A total of 70 biopsies were obtained .
54 were positive (77.1%) and 16 negative (22.9%).
57/70 random biopsies were carried out : 44/57 positive (77.2%) and 13/57 negative (22.8%).
13/70 targeted biopsies performed: 10/13 were positive for prostate adenocarcinoma (76.9%); 3/13 were negative (chronic inflammation) (23.1%).
In 6/13 patients pathology sampling revealed prostate adenocarcinoma with Gleason score 6 (3 + 3) and Gleason score 7 (4 + 3) in 4/13.
The percentage of positivity obtained with random biopsy (12 cores) was 77.2%.
The diagnosis of prostate carcinoma obtained with fusion biopsy (4 cores) was positive in 76.9% and target lesions scanned with mpMRI.
No major or minor complications were observed.
The deviation between the two techniques was 0.3%.
The difference between the two methods for diagnostic purposes seems to be meaningless However we should consider that the high number of cores obtained the high procedure related complications may appear (e.g: hematuria,
neuro-vascular bundle lesions).
For further insights in the poster topic please mail to:
1) Faiella ESantucci DGreco FFrauenfelder GGiacobbeMuto GZobel BBGrasso RF
Analysis of histological findings obtained combining US/mp-MRI fusion-guided biopsies with systematic US biopsies: mp-MRI role in prostate cancer detection and false negative.
Radiol Med. 2017 Oct 10.
2) Fusco RSansone MGranata VSetola SVPetrillo A.
A systematic review on multiparametric MR imaging in prostate cancer detection.
" Istituto Nazionale Tumori - IRCCS - Fondazione G.
Infect Agent Cancer. 2017 Oct 30;12:57.
3) Galosi ABMaselli GSbrollini GDonatelli GMontesi...