Fig. 3: HCC in NAFLD.
75-year-old male with HCC in non-cirrhotic liver with mild steatosis and no steatohepatitis. HCC (white arrow) showing peripheral APHE, no PVWO and some DPWO. Note absence of capsule and a central region of hypo enhancement suggestive of necrosis (*). Resected Specimen showing HCC with central necrosis (dashed arrow. Histology showed a well-differentiated HCC.
Fig. 4: HCC in NAFLD.
73-year-old male patient with HCC in severe steatohepatitis but no cirrhosis.HCC (arrow) shows heterogeneous APHE with no PVWO, DPWO or capsule.
Fig. 6: HCC in NAFLD
80-year-old male with HCC in non-cirrhotic NAFLD with mild steatosis only. HCC (arrow) shows APHE, no PVWO but some DPWO and no capsule. Histology confirmed a well differentiated HCC.
Fig. 2: HCC in NAFLD.
70-year-old male with BMI of 30.7, diabetes and dyslipidemia. Note the prominent and enlarged left lobe. There were no other features suggestive of cirrhosis. Biopsy showed only mild steatosis but no steatohepatitis. HCC (white arrow) shows APHE, no PVWO but with DPWO and no capsule. Histology showed a well differentiated HCC.
Fig. 5: HCC in NAFLD (Inter reader agreement.
47-year-old female with HCC in non-cirrhotic liver with minimal steatosis and moderate steatohepatitis. All 4 readers agreed on APHE and 3 readers agreed on no PVWO and no DPWO. One reader read it as both PVWO and DPWO present. Histology showed moderately differentiated steatohepatic variant of HCC.