Aims and objectives
Our aim was to compare the performance of kinetic imaging in X-ray angiography and the current gold standard digital subtraction angiography (DSA).
Methods and materials
We enrolled 42 patients between February and June 2017.
Eligibility criteria were: symptomatic (Fontaine stage II or III) peripheral arterial disease (PAD) and glomerular filtration rate over 60 mL/min /1.73 m2.
The number of the patients was determined by increasing the minimal recommendation of the U.S.
Food & Drug Administration by 33% .
We performed lower limb angiography according to our institutional protocol,
using a Siemens Artis Zee (30x40 cm detector,
Siemens Healthcare GmbH) and a Syngo workstation (Siemens Syngo XWP...
SNRs were compared in 1902 ROI pairs of 110 images.
An SNR was calculated for each ROI pair,
and the SNRs of kinetic images were divided by the SNRs of sumDSA images.
Table 1 lists the medians of these SNR ratios and shows the fold increase in SNR of kinetic images compared with the DSA images.
Medians were calculated instead of mean values to avoid distortion caused by any outliers.
To demonstrate the effect of post-processing on kinetic image quality,
Kinetic imaging can be used on image series acquired with existing angiography protocols and provides similar information to digital subtraction angiography but with an improved signal-to-noise ratio and higher image quality.
Kinetic imaging may be a new and safer alternative of DSA as used in the last decade in angiography.
Ruzicka FF (1980) Computerized fluoroscopy: digital subtraction for intravenous angiocardiography and arteriography.
AJR Am J Roentgenol 135 (6):1131-1140.
MacIntyre WJ (1980) Digital subtraction angiography of the human cardiovascular system.
AJR Am J Roentgenol 135 (6):1153-1160.