Keywords:
Cardiovascular system, Vascular, MR-Angiography, Technical aspects
Authors:
P. Talarczyk, J. Weir-McCall, L. Brown, J. Summersgill, M. Bonnici-Mallia, S. C. Chin, F. khan, G. Houston; Dundee/UK
DOI:
10.1594/ecr2018/C-2403
Results
The right carotid femoral path length formula after backward linear regression was:
100.36+(0.70×Age[years]) + (137.81×Height[m]) + (0.51×Weight[kg]) - (0.18×heart rate [bpm]) + (46.25 [if female],53.89 [if male])
After excluding those with missing data required for the formula or for PWV calculation the final analysis included 929 SUMMIT participants.
There were significant differences between PWV between three European sites (Dundee,
Exeter and Pisa,
participants >62 years of age) using both PWVSUMM (F-test 19.4,
p<0.001) and PWVMRA (F-test 17.4,
p<0.001).
The strong determinants of PWV (age,
sex and mean arterial pressure) varied significantly between the centres.
After correcting for distribution of these determinants the significant differences in PWV between sites remained for PWVSUMM (F-test=24.4,
p<0.001) but have significantly reduced for PWVMRA (F=5.0,
p=0.007).
There were significant differences between PWV between four European sites (Dundee,
Exeter,
Pisa and Caerphilly,
males >65 years of age,
free from cardiovascular disease) using both PWVSUMM/CApS (F-test=2.8,
p<0.04) and PWVMRA (F-test 3.0,
p<0.03).
After correcting for distribution age,
sex and mean arterial pressure,
differences in PWV between sites remained significant for PWVSUMM/CApS (F-test=4.6,
p<0.004) but were no longer significant for PWVMRA (F=1.4,
p=0.24).
PWV technique |
SUMMIT site 1 |
SUMMIT site 2 |
SUMMIT site 3 |
CAPS Site 4 |
differences |
differences |
Number |
279 |
194 |
262 |
|
Uncorrected |
Corrected |
PWVSUMM
|
11.4 ± 2.5 |
12.1 ± 2.9 |
10.5 ± 2.3
|
|
F=19.4,
p<0.001
|
F = 24.4,
p<0.001 |
PWVMRA |
11.1 ± 2.4
|
10.4 ± 2.3
|
9.9 ± 2.5
|
|
F=17.4,
p<0.001
|
F = 5.0,
p=0.007 |
Number |
110 |
33 |
70 |
705 |
|
|
PWVSUMM/CAPS |
11.4 ± 2.3 |
12.0 ± 2.9 |
10.5 ± 2.1 |
11.5 ± 2.9 |
F=2.8,
p=0.04 |
F=4.6,
p=0.004 |
PWVMRA |
11.0 ± 2.1 |
10.5 ± 2.2 |
9.8 ± 2.0 |
10.6 ± 2.6 |
F=3.0,
p=0.03 |
F=1.4,
p=0.24 |
Table 2.
PWV across the sites with significance of differences between the centres