Keywords:
Breast, Radioprotection / Radiation dose, Mammography, Digital radiography, Conventional radiography, Computer Applications-3D, CAD, Cancer, Dosimetric comparison
Authors:
S. Sethi1, E. Dhamija2, M. yadav2, S. Thulkar3, A. Gupta2; 1delhi, delhi/IN, 2New Delhi/IN, 3NEW DELHI, DELHI/IN
DOI:
10.1594/ecr2018/C-2541
Methods and materials
Patient selection
Retrospective study was conducted in patients presenting to breast cancer clinic in our institution from April 2016 to October 2016.
Patients complaining of breast lump or breast pain were enrolled.
All the patients with previous breast surgery or on chemotherapy were excluded.
Study design and Image interpretation
Mammograms were done using Hologic Selenia Dimensions® in COMBO-HD mode.
The COMBO-HD mode acquires both DBT and SFFDM images in the same compression and generates the synthesized views (C-View 2D image).
This resulted in two sets of mammograms for each patient-SFFDM with DBT and synthesized mammograms (SM) with DBT.
These were evaluated by two experienced radiologists (of experience>5yrs) jointly and the findings were recorded as consensus from both.
The radiologists were blinded for patients demographics,
clinical details,
sonographic and histological results as well as whether they were evaluating standard view or synthesized view.
Breast densities (classified as ACR-A/B/C/D according to Breast Imaging Reporting Imaging and Data System BI-RADS),
lesion characterization (density,
shape,
margin),
calcification(presence,
distribution),
asymmetry,
architectural distortion and BI-RADS scale assessment were evaluated individually for all lesions.
Average glandular dose (AGD) and effective surface dose (ESD) of each breast were recorded separately.
Statistical analysis
Statistical analysis was performed by using software SPSS (version 16.0).
Multivariate analysis was done using chi square 2 test.
A p value of <0.05 was considered as statistically significant difference.
T-test (paired) was used to compare AGD and ESD of FFDM and SM,
both along DBT.