Education and training, Education, CT-High Resolution, CT, Thorax, Mediastinum, Lung
G. Bittencourt Basso, D. Moreira Furlanetto, A. Marchini da Silva, V. Sanchez Lajarin, J. Amorim Teixeira Grill, H. Pereira, D. Borges Montel, D. Guimaraes Faria, H. M. H. Lee, C. Gomes dos Reis; São Paulo/BR
Immune-mediated diseases are a group of unrelated conditions with a common inflammatory pathway.
The thoracic manifestations of these diseases are diverse.
All the compartments can be independently or simultaneously affected,
including the respiratory tract,
all cardiac structures and musculoskeletal sites,
depending on the pathophysiologic aspects of the underlying disease process. The most relevant immune-mediated diseases that involves the chest are summarized on Table 1.
It is necessary to exclude the possibility of thoracic complications related to the drug therapy,
as well as opportunistic infections caused by immunosuppression,
before establishing a diagnosis of chest involvement secondary to immune-mediated diseases.
The most common thoracic manifestations are interstitial lung diseases,
being also the major causes of morbidity and mortality in these patients.