Keywords:
Image registration, Molecular imaging, PET-CT, Nuclear medicine
Authors:
D. Faria, J. Vale, C. Dias, L. Rodrigues, L. Ferreira, P. M. Martins; Aveiro/PT
DOI:
10.1594/ecr2018/C-3186
Methods and materials
62 patients,
47 males,
13 females,
aged 41 to 85 years,
mean age of 64 ± 11,6 years,
with a total of 74 increased F-18-FDG uptake lesions where included.
Data was acquired on a GE Discovery LS/4 PET-CT Scanner starting 60 to 90 minutes after the i.v.
administration of 18F-FDG (5 MBq/Kg of patient weight); CT acquisition used 120 kV,
80 mA and 1.5 pitch and PET acquisition on 2D mode included 5 to 6 FOV (3 minutes per bed position).
A further 1 to 2 late FOV (> 2 hours p.i.) acquisition was undertaken with attenuation maps with CT,
120 kV,
80 mA and 1.5 pitch,
in forced inspiration and expiration and shallow breathing.
PET images were acquired in 2D mode,
1 or 2 FOV/5 minutes,
in shallow breathing.
Three emission sets were reconstructed with Ordered Subsets Expectation Maximization (OSEM) and Measured Attenuation Correction (MAC).
Lesions where classified as right-upper-lung(RUL),
left-upper-lung(LUL),
right-medial lung(RML),
left-medial-lung(LML),
right-lower-lung(RLL),
left-lower-lung(LLL) and liver(LIV).
Image registration was evaluated as correct/wrong and the number of mismatch transaxial slices were determined based on axial PET images.
SUVmax value of each lesion was determined for each set of reconstructed images with the different attenuation maps obtained.