Aims and objectives
Accordingly to the data of Kazakh Scientific Research Institute of Oncology and Radiology,
in Kazakhstan rectal carcinoma (RC) keeps the 8th position in cancer morbidity rate (4,5% or 8,2 cases per 100000 of population),
and the 8th position in cancer-related mortality rate as well (4,7%) .
Despite the fact that these indexes are lower comparing with the similar data from developed countries (the forth most frequently diagnosed cancer,
and the second leading cause of cancer-related death [2,3]),
growing morbidity rate,
especially in population younger than...
Methods and materials
This study included 86 patients (46 men,
mean age 61,7±12,9 years) with a new diagnosis of rectal carcinoma established on site at the Kazakh State Institution of Oncology and Radiology,
between January 2015 and June 2018.
The study was approved by the institutional review board.
The inclusion criterion was a new diagnosis of path-proved rectal carcinoma below the sacral promontorium with no gender or age predilection.
MRI was performed using a 3.0-T system pre-operatively (GE Discovery MR750w,
Evaluation of tumor staging according to MRI data in comparison with histopathological data
The results of preoperative MRI staging and postoperative pathology T-staging are presented in Table 1.
The discrepancy between the MR and pathological staging was noted by us in 16 cases out of 86.
An analysis of the discrepancy between the results is shown in Table 2.
There were following cases of overdiagnosis (reassessment of the stage) of the process according to MRI (see table 2):
· In one case,
on the pathomorphological...
3T MRI imaging enables to achieve high levels of diagnostic accuracy in local rectal cancer staging,
including assessment of mesorectal fascia infiltration.
The reasons over- or underestimation of all the stages were analyzed and compared with the results of similar studies.
High-resolution MRI can clearly differentiate EMVI-status with high accuracy as well,
evaluating this important risk factor for early recurrence and tumor aggressiveness.
[dataset]  Oncology service statistics review (statistic data of Kazakh State Institution of Oncology and Radiology)/ under rev.
 Benson AlB,
Clinical practice guidelines in oncology.
Journal Natl Compr Canc Netw 2018; 16(7): 874-901.
Caseiro-Alves F et al.
Magnetic resonance imaging for the clinical management of rectal cancer patients: recommendations from the 2012 European Society of Gastrointestinal and Abdominal Radiology (ESGAR) consensus meeting....