Education and training, Diagnostic procedure, MR-Cholangiography, MR, CT, Pancreas, Biliary Tract / Gallbladder, Abdomen
J. Miguez Gonzalez, P. LOZANO ARRANZ, R. Oliveira Caiafa, F. Calaf Forn, A. Thomas, J. Catala Forteza; Barcelona/ES
Autoimmune Pancreatitis and IgG4-Related Sclerosing Cholangitis are the two main ways of pancreatic and biliary involvement in IgG4-Related Disease.
They have distinctive radiological features on CT and MRI (Fig. 22) that must be known by the radiologist in order to allow an early diagnosis and an optimal therapeutic approach,
avoiding misdiagnosis with other diseases and unnecesary invasive procedures.
Both entities are associated in up to 80-90% of cases and share clinical symptoms,
presenting usually as a painless or mildly symptomatic obstructive jaundice in a 40 to 70 year-old man with elevation of serum levels of IgG4 and dramatic response to steroids (Fig. 23).
The presence of IgG4-related disease in other organs is not uncommon and supports the diagnosis.