Aims and objectives
In Japan,
cerebrovascular disease is the fourth cause of death and the first cause of bedridden patients1).
Recently,
cerebral stroke has been under serious consideration due to the westernization of the diets and an increase in geriatric diseases.
At present,
cerebral stroke is still one of the most important diseases to control and prevent ( Fig. 1 ).
To establish a method for image-based diagnosis of cerebral stroke,
the authors developed a phantom that could correctly evaluate disease detection by image-processing and that could visualize...
Methods and materials
1.
Development of phantom to cerebral infarction
Using a Cerebral Infarction phantom,
which had been developed by the authors (Kyoto kagaku,
JPN),
an imitation disease with 34 HU was set to be visualized.
The phantom,
prepared with polyurethane resin and epoxy resin,
the developed phantom mimicked the head shape and was composed of three sections: brain,
cranium,
and imitation disease.
In the brain section,
sphere-shaped imitation diseases (acute-stage cerebral infarction) of 30 mm in diameter were allocated in the middle cerebral artery region.
The CT...
Results
1.
FIRST images
Fig. 6 ,
Fig. 7 ,
and Fig. 8 shows the simulation results of each Forward projected model-based Iterative Reconstruction Solution images.
Both FIRST Brain and FIRST Brain LCD can observe a significant reduction in noise as the intensity of image reconstruction increases.
Furthermore,
this tendency appeared remarkably in FIRST Brain LCD rather than FIRST Brain.
Focusing on the difference in slice thickness,
The slice thickness of 1 mm had less image blur than the slice thickness of 5 mm,
and the...
Conclusion
We were able to detect acute ischemic stroke at its early stage by using Iterative Reconstruction in X-ray CT to apply Forward projected model-based Iterative Reconstruction Solution imaging to a phantom.
CNRLO exceeding FBP was FIRST Brain LCD of standard and strong,
and Considering the FOM,
approximately 400 and 600 mA is good.
FIRST in CT images could be used clinically to judge whether thrombolytic therapy with the use of rt-PA is applicable to acute-stage cerebral infarction. Therefore,
optimal conditions for visualizing acute-stage cerebral infarction...
Personal information
Hidetake Hara,
Ph.D.,
RT
Department of Radiology,
School of Allied Health Sciences,
Kitasato University in JAPAN
eMail:
[email protected]
References
[1]Ministry of Health,
Labour and Welfare secretariat statistics and information department,
vitalstatistics.
2017.
http://www.mhlw.go.jp/toukei/saikin/hw/jinkou/geppo/nengai17/index.html.
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Hara,
H.
Muraishi,
T.
Inoue,
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IFMBE Proc.
Vol.39,
831-834,
2012.
[3] H.
Hara,
T.
Inoue,
Y.
Nakajima: Development of an X-ray CT Phantom for Evaluation of Cerebral Apoplexy.
The St.Marianna Medical Journal,
Vol.38,
9-16,
2010.
[4] H.
Hara,
H.
Muraishi,
T.
Inoue,
et al.: Dual-Energy Computed Tomography Technique Aiming at Visualization of Acute Cerebral Infarction....