Aims and objectives
Demonstrate the utility of 18F-FDG PET CT for the localization of tumors of unknown primary origin.
Assess the most common histopathological lineage of primary tumor detected by 18F-FDG PET-CT in our hospital.
Methods and materials
*83 patients referred to the PET-CT department with clinical diagnosis of probable unknown primary tumor were included.
*PET-CT findings were correlated with the results of follow-up and/or histopathology report.
The results obtained in this study were concordant with the literature,
being the negative predictive value of PET-CT the highest value in case of patients with tumors of unknown origin; all this can be attributable to the poor indication of PET-CT (without a previous exhaustive clinical study or without previous biopsy).
The most common histopathological lineage of primary tumor detected by 18F-FDG PET-CT in our hospital was poorly differentiated adenocarcinoma.
Despite the high rate of false positives,
the detection of true positives is important,
for this reason PET-CT is considered useful for the evaluation of patients with suspected metastatic tumors of unknown origin; increasing its value when it correlates with the clinical assessment and there is a well-founded suspicion.
Combined FDG-PET/CT for the detection of unknown primary tumors: systematic review and meta-analysis.
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