Keywords:
Interventional non-vascular, Musculoskeletal soft tissue, Musculoskeletal system, MR, Percutaneous, Ultrasound, Efficacy studies, Treatment effects, Biological effects, Outcomes
Authors:
M. E. E. Mostafa Fouad, A. A. M. B. Okba; Cairo/EG
DOI:
10.26044/ecr2019/C-1482
Results
For the whole study group members: an exploratory analysis of SPADI scores prior to the procedure,
at 6 weeks,
and at 3 months after the procedure included data of only eligible patients.
Data of 10 patients were analyzed.
The total scoring difference between pre-injection and post-injection SPADI scores was highly statistically significant (P < 0.001) at 6 weeks and 3 months (Table 1,
Figure 5).A statistically significant improvement of the total scores and their percentages should be concluded from the following scores.
They showed remarkable drop from a mean value ± SD of 95.90 ± 8.06 (73.50 ± 6.17 %) (Baseline values) to 66.80 ± 5.05 (51.50 ± 3.81%) after 6 weeks (post-injection),
completing its descending way to 59.30 ± 10.22 (45.70 ± 8.00 %) after 3 months.
The P value of <0.001 suggested high statistical significance difference between the value before PRP injection versus at 6 weeks and 3 months follow up points.
However,
the P value was significant evidenced by a value of 0.025 throughout the duration between 6 weeks and 3 months post-procedure follow up dates.
For the intra-articular supraspinatus partial tendon tear subgroup members, data of 8 patients were analyzed.
The total scoring difference between pre-injection and post-injection SPADI scores was highly statistically significant (P < 0.001) at 6 weeks and 3 months follow up points but they were insignificant (P <0.220) when values were acquired throughout the period between both re-assessment dates (Figure 6).
According to the aforementioned results,
a statistically significant improvement of the total scores and their percentages could be noted,
supported by the remarkable decrease from a mean value ± SD of 98.17 ± 0.41 (75.17 ± 0.41%) (Baseline values) to 67.33 ± 2.58 (51.83 ± 2.04 %) after 6 weeks (post-injection),
completing its decline,
albeit with a slower rate,
to 65.00 ± 2.00 (50.17± 1.60 %) after 3 months.
The P value <0.001 suggested high statistical significance before PRP injection versus after 6 weeks and 3 months follow up points.
However,
the P value was insignificant evidenced by a value of 0.220 (for the percentages P = 0.267) throughout the duration between 6 weeks and 3 months post-procedure follow up dates.
For the intra-substance supraspinatus partial tendon tear subgroup members, data of two patients were analyzed.
The statistical analysis showed that there was a statistically significant improvement of the pain score in the baseline mean value ± SD versus after 3-month post-injection follow up,
where the pain score dropped from 36.50 ± 2.12 to 19.50 ± 0.71 and confirmed by P value = 0.037.
Otherwise,
all other statistical values illustrated insignificant P values,
in spite of clinical improvements in all the scores including the pain,
the disability,
the total scores and their percentages (Figure 7).