Aims and objectives
Soft tissue sarcomas/tumors (STSs) are a diversified class of neoplasia that have diagnostic and therapeutic problems for clinical care (1).
DWI has been presumed to have the ability to discriminate between benign and malignant soft-tissue tumors because malignant tumors have more cellularity and therefore have more restricted diffusion than benign tumors (2).
The diagnosis of such masses remains a challenge for the clinician because malignant and benign tumors,
as well as non-neoplastic masses following inflammation or trauma,
have a similar presentation (3).
MRI is the...
Methods and materials
The study population included 90 patients presenting with extremity soft tissue masses for an initial assessment at the National Cancer Institute in Egypt.
The study has been approved by the ‘‘Ethical Committee of Faculty of Medicine,
in compliance with Helsinki Declaration.
The patients’ ages range from 1 to 75 years with the mean age of 36 years.
We performed a prospective lesion-based analysis for 108 newly diagnosed soft tissue lesions.
We also include post-therapeutic imaging follow up for 18 patients.
Magnetic resonance imaging:...
The study included 108 newly diagnosed soft tissue lesions.
Their histologic diagnoses were as follows:
Fibromatosis (n=42),dermatofibrosarcoma protuberans (n=4),
lipoma (n=9) ,
hemangioma (n=5) schwannoma(n=1),
GCT tendon sheath(n=1)/ synovial sarcoma (n=6)/ rhabdomyosarcoma (n=7),
undifferentiated sarcoma (n=7)/ malignant melanoma (n=2),
squamous cell carcinoma (n=3)/ mucor fungoides (n=1),
high grade sarcoma (n=3),
low grade sarcoma (n=2),
malignant nerve sheath tumor (n=1),
Our study results demonstrated that benign soft tissue masses had a mean...
Regarding inital evaluation of soft tissue masses
A significant overlap between benign & malignant masses as benign & malignant ADC values were (mean ADC=1.2 x 10-3 mm2/sec & 1.31 x 10-3 mm2/sec ,respectively).
Mean ADC values for benign non myxoid tumors,
myxoid malignant tumors & non myxoid malignant tumors were 1.2× 10-3 mm2/sec,
2.6× 10-3 mm2/sec & 1.1× 10-3 mm2/sec.
Newly diagnosed fibromatosis patients mean ADC values were 1.31 ± 0.25 × 10-3 mm2/sec)
Regarding post-therapeutic follow up
Follow up soft tissue sacromas patients showed...
1. Afonso PD,
Following unenhanced MRI assessment for local recurrence after surgical resection of mesenchymal soft tissue tumors,
do additional gadolinium-enhanced images change reader confidence or diagnosis?.
Eur J Radiol 2013;82:806‑13.
2. Maeda M,
Soft-tissue tumors evaluated by line-scan diffusion-weighted imaging: influence of myxoid matrix on the apparent diffusion coefficient.
J Magn Reson Imag 2007; 25:1199–204.
3. Andreas MH,
Top Magn Reson Imaging 2007; 18:203-212.
4. Koh DM,