Role of Baseline Spectroscopy and ADC Biomarkers as Early Recurrence Predictors in Patients with Glioblastoma.

Congress:

ECR 2019

Poster Number:

C-2196

Type:

Scientific Exhibit

Keywords:

Neuroradiology brain, MR, MR-Spectroscopy, MR-Diffusion/Perfusion, Diagnostic procedure, Intensity Modulated Radiotherapy (IMRT), Treatment effects, Outcomes, Cancer, Multidisciplinary cancer care

Authors:

N. Dichko¹, Y. Kmetyuk², K. A. Musaieva², O. Silaieva²; ¹Kyiv/UA, ²Kiev/UA

DOI:

10.26044/ecr2019/C-2196

DOI-Link:

https://dx.doi.org/10.26044/ecr2019/C-2196

Conclusion

Baseline Glioblastoma MRS parameters have predictive potential in early vs late recurrence patient stratification.

The predictive capacity of acquired logistic regression model provides the possibility to develop a scoring system by weighting dummy-coded variables and assigning scores to each MRSI and DWI parameter. Therefore we plan on inter-institutional expansion of the study cohort to apply the scoring system of acquired cut-offs and validate the accuracy in a prospective multi-institutional study.