Keywords:
Head and neck, Neuroradiology peripheral nerve, MR, Experimental investigations, Outcomes
Authors:
M. Cellina1, M. A. Orsi1, E. Belloni2, F. Calliada3, C. Floridi4, M. Pirovano1, M. Ciocca1, G. Oliva1; 1Milan/IT, 2Vigevano (Pavia Province)/IT, 3Pavia/IT, 4Perugia (PG)/IT
DOI:
10.26044/ecr2019/C-2451
Aims and objectives
Optic neuritis (ON) is an acute inflammatory demyelinating disorder,
primarily an isolated phenomenon or secondarily associated with other neurological diseases as neuromyelitis optica or multiple sclerosis (MS) [1].
Its most common symptoms include unilateral,
subacute visual loss with variable degree of severity,
periocular pain on eye movements,
dyschromatopsia,
without systemic or other neurological symptoms.
The presentation is mostly monophasic but can also rarely be polyphasic with recurrent relapses.
ON is most frequently seen in females,
F:M=3:1,
diagnosed in young adults aging 20-45 years; mean age at onset is 36 years.
ON may be the initial presentation in ~20% of MS patients,
and ON may occur during the course of the disease in 50% of patients with MS.
ON is normally a self-limiting event and recovery of visual acuity typically occurs within the first few weeks of symptom onset,
however some patients have persistent visual problems [2,3].
Magnetic Resonance Imaging (MRI) may help ON diagnosis by detecting optic nerve inflammation.
Application of MRI to the assessment of optic nerve damage in a single episode of acute ON has been performed rarely [4] and its role in predicting the prognosis of visual impairment is not clear [3,
4].
Therefore,
our aim was to assess MRI findings in the acute phase of ON and their correlation with visual acuity at presentation,
visual outcome,
MS development