Type:
Educational Exhibit
Keywords:
Neoplasia, Metastases, Education and training, Education, Diagnostic procedure, MR-Spectroscopy, MR-Diffusion/Perfusion, MR, Paediatric, Oncology, CNS
Authors:
T. M. B. Da Conceição1, F. Dossin2, F. Pereira dos Santos2, B. C. Chwal2, M. Dorigatti Soldatelli2, J. Ávila Duarte2; 1Porto Alegre, RS/BR, 2Porto Alegre/BR
DOI:
10.26044/ecr2019/C-2512
Background
We report the magnetic resonance imaging findings of a series of cases from the experience of patients diagnosed with medulloblastoma in the 15 years experience of the Neuroradiology service at Hospital de Clínicas,
Porto Alegre,
RS,
Brazil.
The peak of occurrence is between 5-7 years of age,
with 70% of them occurring under 16 years.Neuroimaging studies play an important role in the diagnosis and staging of medulloblastoma,
in assessing the degree of resection,
follow-up,
and recurrence.
Magnetic resonance imaging (MRI) is more sensitive in the evaluation of tumor characteristics,
such as size,
location and spinal neoplasm.
The diffusion study (DWI) and magnetic resonance spectroscopy may suggest the specific molecular subgroup.
The prognosis depends on the success of surgical resection,
the presence of CSF metastasis at the time of diagnosis and c-erbB-2 (HER2 / neu) oncogene expression.
In recent years,
with the advancement of molecular medicine,
we have discovered a large number of distinct molecular subgroups [4].
The 2016 update of the WHO classification of CNS tumors,
which recognizes four molecular subgroups: medulloblastoma - WNT,
medulloblastoma - SHH,
medulloblastoma - group 3,
medulloblastoma - group 4.