Keywords:
Cancer, Radiation therapy / Oncology, PET-CT, CT, Nuclear medicine, Lung
Authors:
S. L. Kure1, M. Petersen2, T. Hansen 3; 1Tjæreborg/DK, 2Esbjerg Ø/DK, 3Vejle /DK
DOI:
10.26044/ecr2019/C-2863
Aims and objectives
The aim of the litterature study was to compare research which use fused PET/CT for planning of radiotherapy and permit an increased radiation dose to the malignant tissue.
Common to the included projects was that they focused on the metabolic charging of FDG in the scan to define the tumor volume.
By defining the active volume of the tumor,
studies have shown that it will be possible to change the threatment dose in different ways.
Either by reducing the PTV (planned tumor volume) to only cover the FDG active part of the tumor or escalate the dose to the whole tumor with or without a additional boost the the active area of the tumor.
However by increasing the dose,
the risk of severe acute and late sie effects increase as well as a result of the increased dose to the surrounding OAR (Organ at risk).
Therefore a change in dose might not always give a better outsome for the patient.
To incorporate this,
the studyn compared the different methods,
and investigated how they affect the dose,
the size of the target volume and the patient outcome.