Abdomen, Pancreas, Oncology, MR, MR-Diffusion/Perfusion, Diagnostic procedure, Imaging sequences, Tissue characterisation
F. Donati1, P. Boraschi1, F. Pacciardi1, R. Cervelli2, G. Tarantini1, C. Lombardo1, U. Boggi1, F. Falaschi1, D. Caramella1; 1Pisa/IT, 2Pisa, It/IT
Aims and objectives
Differentiation of ductal adenocarcinoma from mass-forming pancreatitis is a continuing challenge for the radiologist.
this differential diagnosis is considerably difficult particularly with a single imaging modality.
Diffusion-weighted (DW) MRI is becoming increasingly important in the assessment of malignant tumors providing information about the biophysical properties of tissues.
Several studies have reported that ADC can contribute to the differential diagnosis of benign and malignant focal lesions.
contrast-enhanced Perfusion (CE-PW) MRI can improve the sensitivity and specificity of diagnostic imaging,
providing information concerning the vascular density,
and integrity the vascular wall.
This information can be applied to studies of angiogenesis and biomarkers.
Preliminary studies support a possible role of Perfusion MRI in the evaluation of abdominal organs,
specially pancreas and pancreatic pathologies.
The purpose of our study was to assess the usefulness of combined DW MRI with CE-PW MRI at 3T-device in the differential diagnosis of solid pancreatic lesions.