Neuroradiology spine, Musculoskeletal spine, Interventional non-vascular, MR, Imaging sequences, Treatment effects
F. Bruno, P. Palumbo, M. V. M. Micelli, A. Izzo, M. Varrassi, A. Splendiani, C. Masciocchi; L'Aquila/IT
Methods and materials
We evaluated 28 patients (15 male,
48.9 ± 9.6 years,
range 25-61) with sciatica from single-level lumbar disc herniation (L3-L4,
4 patients; L4-5,
13 patients; L5-S1,
eligible for O2-O3 chemiodiscolysis treatment.
All patients underwent 3T MR scan with standard morphological and T2 mapping sequences,
before and one month after treatment.
Instrumental imaging evaluation included analysis of intervertebral disc area (fig.1) and analysis of T2 relaxation time maps with ROI position at the affected disc level (fig.2).
All patients were evaluated one month after treatment with MRI to assess the reduction of disc area.
Clinical evaluation using the VAS scale for pain and the Oswestry Disability Questionnaire for functionality was performed before treatment and with a 1-month follow-up in all patients.
Our results were compared to a control group of 25 patients with lumbosciatica who were submitted to conservative treatment.
Statistical analysis was performed for comparison and correlation of variables