128 patients were included in this study,
with age ranging from 27 to 83 years,
with the mean age (±SD) of 57,7 (±14,4) years.
10 patients have had more than one procedure with total number of aneurysms studied – 143.
Most common of material types that were used in cerebral aneurysm embolization in both groups are seen in Figure 5.
Number of patients in the rupture group was 99 (with a total of 99 aneurysms) – 59 women (59,6%) and 40 men (40,4%) with the mean age of 55,9(±14,1) years.
The most common localization of embolized ruptured aneurysms in 33 (33%) cases was anterior communicating artery (Figure 6) which coincides with data found in other studies.
[3,4,5] The degree of occlusion immediately after treatment was evaluated as Montreal A in 77 (77,8%) cases,
Montreal B in 18 (18,2%) cases,
and Montreal C in 4 (4%) cases with the mean packing density of 33%.
The result of the treatment was re-evaluated three to six months after procedure.
23 patients missed the control angiography and 18 had died.
Follow-up group consisted of 58 patients with following results - the degree of occlusion did not change in 42 (72,4%) cases,
worsened in 9 (15,5%) cases,
and improved in 7 (12,1%) cases.
Complete occlusion (Montreal A) after embolization and during follow-up in the majority of cases was achieved by using coils together with balloon catheter,
stent or both (Figure 7).
The unruptured aneurysm group consisted of 38 patients – 26 women (68,4%) and 12 men (31,6%) with a total of 44 aneurysms.
Age range in this group was 40 to 76 with the mean age of 57,7(±10,2) years.
The most common localization of embolized unruptured aneurysms in 21 (48%) cases was middle cerebral artery (Figure 6).
After embolization,
32 (72,7%) aneurysms were evaluated as Montreal A,
10 (22,7%) as Montreal B,
and 2 (4,5%) as Montreal C with the mean packing density of 39%.
During first follow-up,
the degree of occlusion did not change in 21 (84%) cases,
worsened in 2 (8%),
and improved in 2 (8%) cases.
The follow-up evaluation was not performed in 19 patients,
which were not considered in these calculations.
Complete occlusion (Montreal A) after embolization and during follow-up in the majority of cases was achieved by using coils together with balloon catheter,
stent or both (Figure 8).
To assess correlation between coil packing density and degree of occlusion,
Kruskal-Wallis test was used.
It was concluded,
that no statistically reliable correlation could be found in both ruptured and unruptured groups.
The relevant p values for the acute patient group were p=0,523 immediately after coiling and p=0,208 in the follow-up,
and for the unruptured group p=0,078 and p=0,605 respectively.