Not applicable, Experimental, Education and training, Technical aspects, Chemotherapy, Arterial access, Percutaneous, Catheter arteriography, Oncology, Interventional vascular, Eyes, Interventional Radiology
P. A. Rago1, J. Bartuszek2, E. Jurkiewicz1, U. H. Pasik1, J. Debska1; 1Warsaw/PL, 2Warszawa/PL
Retinoblastoma is the most common intraocular tumor in childhood. For a long time enucleation, radiation and systemic chemotherapy was the only way to accomplish full recovery. Nowadays we have developed and mastered a modern method of treating retinoblastoma – intraarterial chemotherapy through ophthalmic artery, right to malignancy in retina.
Intraarterial chemotherapy (IAC) is an invasive procedure and, in our institute, it is performed by an interventional radiologist in cooperation with an ophthalmologist. The ophthalmologist is the one who qualifies the patient for the procedure and performs complementary treatment including : cryotherapy and laser therapy. In some cases systemic chemotherapy is needed. The only conditions for the radiologist in this matter is the weight of the child, and consequently its age and the anatomical variants – for now we did perform the procedure with children under 4 months, and under 6kg. Secondary approach for IAC through anastomosis with middle meningeal artery had been mastered for children with insufficient anatomical conditions for standard IAC approach.
In Europe many centers started to provide this treatment for their patients in the last years.
Purpose of this research was to analize and share our results, experience, failures, and changes from many aspects like training, experience, technical aspects of catheterization and chemotherapeutic agents doses, dilution and administration