Learning objectives
To review computed tomography (CT) Imaging appearance of commonly seen hepatic focal lesions in our practice and correlate them with their imaging features in magnetic resonance imaging (MRI).
To understand MRI protocol and how to make the best use of each sequence.
To give a thematic answer to the juniors regarding the question: when do we order MRI (conventional, post-contrast and advanced sequences) in our radiological US/CT reports for better evaluation of hepatic focal lesions?.
Background
With the widespread of cross-sectional imaging, growth in the rate of incidentally detected focal liver lesions (FLL) has been observed. Reliable detection and characterization of FLL are critical for optimal patient management. The majority of FLL arising in the noncirrhotic liver are benign including Cysts, hemangiomas, focal nodular hyperplasias (FNH), and hepatocellular adenomas (HCA) are the most commonly encountered benign lesions [1].
The most commonly encountered malignant lesions in the noncirrhotic liver are metastases and rarely fibrolamellar carcinoma(FLC). Hepatocellular carcinomas (HCC), and to a lesser...
Findings and procedure details
MRI technique of liver examination at our unit:
The technique is done on a 1.5 Tesla machine.
Conventional sequences
T1WI, T2WI, heavy T2WI, T1 2D/3D gradient echo sequences(vibe),& In-Out phase(chemical shift).
Advanced sequences
liver-specific contrast agents e.g Gd-BOPTA, Dynamic postcontrast, subtraction, DWI& ADC.
In&outphase: based on chemical shift mechanism and works on omitting the intracellular fat specifically.
DWI&ADC: diffusion-weighted images (DWI) performed before the dynamic study to rule out the effect of contrast media on apparent diffusion coefficient (ADC) values. It is also done on...
Conclusion
Multi-parametric merit of MRI gives radiologists much more malleability than other imaging modalities to narrow the differential diagnosis of hepatic focal lesions.
Personal information and conflict of interest
M. Elmansy; Mansoura/EG - nothing to disclose
Mostafa Ahmed Mahmoud Elmansy, Assistant Lecturer, Radiology Department, Mansoura University.
Phone: +201149522327/ Email :
[email protected]
References
1-Nault, J.C., Bioulac–Sage, P. and Zucman–Rossi, J., 2013. Hepatocellular benign tumors—from molecular classification to personalized clinical care. Gastroenterology, 144(5), pp.888-902.
2-Bastati, N., Feier, D., Wibmer, A., Traussnigg, S., Balassy, C., Tamandl, D., Einspieler, H., Wrba, F., Trauner, M., Herold, C. and Ba-Ssalamah, A., 2014. Noninvasive differentiation of simple steatosis and steatohepatitis by using gadoxetic acid-enhanced MR imaging in patients with nonalcoholic fatty liver disease: a proof-of-concept study. Radiology, 271(3), pp.739-747.
3-Fowler, K.J., Brown, J.J., and Narra, V.R., 2011. Magnetic resonance imaging of focal liver lesions:...