Purpose
Breast cancer is the most common cancer among females worldwide [1]. In Jordan, breast cancer accounted for 37.3 % of the cancers in females and ranked the first in all years from 1996-2012 [2-4]. Mammography is the screening modality for early detection of breast cancer. 'Mammographic density’ is a term used to describe the portion of the breast that comprises fibroglandular tissue on mammograms [5]. The high mammographic density is a significant predictor of breast cancer risk and is associated with four- to six-times increased...
Methods and materials
Ethical approval was obtained from Jordan University of Science and Technology and a written consent was obtained from all participated radiologists.
Image test set
A set of 60 digital mammograms (cranio-caudal (CC) and medio-lateral oblique MLO projections) of both breasts were included. The test set contain 20 cases with 21 biopsy proven cancer lesions and 40 cancer free cases confirmed after 2 years follow up.
Images were allocated to specific mammographic densities according to the Australian and New Zealand College of Radiology (RANZCR) synoptic guidelines...
Results
Table 1 shows that radiologists demostrated higher sensitivity (P=0.02), AUC (P=0.01), location sensitivity (P=0.01) and JAFROC FOMs (P=0.01) when reading high compared to low mammographic density cases. Radiologists with under 1000 annual reads had higher AUC (P=0.01), location sensitivity (P=0.03) and JAFROC FOMs (P=0.01) for high compared to low mammographic density. Radiologists with over 1000 annual reads had higher location sensitivity in high compared to low mammographic density cases (P=0.04).
Conclusion
In Jordan, 30% of breast cancer cases are among youngfemales where mammographic breast density is high[4]. Therefore, for this specific population it is very important to accurately detect cancer in breasts with high mammographic density. Our study aimed to investigate radiologists’ performance in both low and high mammographic density cases and to explore whether radiologists with different rates of annual reads perform differently when interpreting cases with different mammographic density.
In conclusion, this preliminary study suggests that radiologists’ performance was superior in high mammographic density...
Personal information and conflict of interest
D. S. Al-Mousa; Irbid/JO - Author at Jordan University of Science and Technology - Speaker at Jordan University of Science and Technology M. Alakhras; Irbid/JO - Author at Jordan University of Science and Technology Rula Abu Taimai; Amman/JO - Author at Jordan Breast Cancer Program Ayat Makhadmeh;Irbid/JO - Author at Jordan University of Science and TechnologyKelly M. Spuur; Wagga Wagga/Aus - Author at Charles Sturt University
Dana Samir Al-Mousa
Department of allied Medical Sciences, Faculty of Applied Medical Sciences, Jordan University of Science and Technology...
References
1.Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68(6):394-424.
2.Jordan Ministry of Health: Annual incidence of cancer in Jordan. Amman: 2009. Available at: http://www.moh.gov.jo/EN/Pages/Periodic-Newsletters.aspx. Accessed July 19, 2019.
3.Jordan Ministry of Health: Annual incidence of cancer in Jordan. Amman: 2012. Avaialble at: http://www.moh.gov.jo/EN/Pages/Periodic-Newsletters.aspx. Accessed June 12, 2019.
4.Jordan Ministry of Health: Jordan cancer registry, Cancer incidence in Jordan. Amman: 2014....